A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of XIST
ncRNA name XIST
ncRNA Category lncRNA
ID 7503
Ensembl ENSG00000229807
Synonyms DXS1089, DXS399E, LINC00001, NCRNA00001, swd66
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples, normal retinas; RB cell lines Y79, WERI-RB1, SO-RB-50 and HXO-RB44
Methods qRT-PCR, CCK-8 assay, cell cycle analysis, apoptosis assay, Western blot, luciferase reporter assay
Expression pattern up-regulated
Functional description XIST promoted RB progression partially by modulating the miR-124/STAT3 axis.
PubMed ID 30114638
Year 2018
Title Knockdown of lncRNA XIST inhibits retinoblastoma progression by modulating the miR-124/STAT3 axis.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.