| ncRNA name | MEG3 |
| ncRNA Category | lncRNA |
| ID | 55384 |
| Ensembl | ENSG00000214548 |
| Synonyms | GTL2; FP504; prebp1; PRO0518; PRO2160; LINC00023; NCRNA00023; onco-lncRNA-83 |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RPE cell line ARPE-19 |
| Methods | transfection, qRT-PCR, Western blot, luciferase assay, ELISA, MTT assay, flow cytometry |
| Expression pattern | down-regulated |
| Functional description | MEG3 could alleviate HG-inducing apoptosis and inflammation via inhibiting NF-κB signaling pathway by targeting miR-34a/SIRT1 axis. |
| PubMed ID | 30529346 |
| Year | 2019 |
| Title | LncRNA-MEG3 alleviates high glucose induced inflammation and apoptosis of retina epithelial cells via regulating miR-34a/SIRT1 axis. |
| Drug-related ncRNA | NO |
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