A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of MEG3
ncRNA name MEG3
ncRNA Category lncRNA
ID 55384
Ensembl ENSG00000214548
Synonyms GTL2; FP504; prebp1; PRO0518; PRO2160; LINC00023; NCRNA00023; onco-lncRNA-83
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line serum; human RPE cell line ARPE-19
Methods qRT-PCR, ELISA, Western blot
Expression pattern down-regulated
Functional description LncRNA MEG3 overexpression may inhibit the development of diabetic retinopathy by inhibiting TGF-β1 and VEGF expression.
PubMed ID 30186476
Year 2018
Title LncRNA MEG3 overexpression inhibits the development of diabetic retinopathy by regulating TGF-β1 and VEGF.
Drug-related ncRNA NO

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