ncRNA name | MEG3 |
ncRNA Category | lncRNA |
ID | 55384 |
Ensembl | ENSG00000214548 |
Synonyms | GTL2, LINC00023, NCRNA00023, onco-lncRNA-83 |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples; RB cell line SO-RB50, Y79 and WERI-RB1 |
Methods | microarray, qRT-PCR, flow cytometry, Western blot |
Expression pattern | up-regulated |
Functional description | The lncRNA profile in RB and adjacent normal tissues were compared by microarray analysis. A total of 7 up-regulated (7SK, DNM3OS, MEG3, HIF1A-AS1, CCAT1, HOTAIR and LSINCT5) and 5 down-regulated lncRNAs (H19, PCAT1, RRP1B, BCAR4 and MIR31HG, > 2 fold) we |
PubMed ID | 28088735 |
Year | 2017 |
Title | Long non-coding RNA CCAT1 promotes human retinoblastoma SO-RB50 and Y79 cells through negative regulation of miR-218-5p. |
Drug-related ncRNA | NO |
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