|GTL2; FP504; prebp1; PRO0518; PRO2160; LINC00023; NCRNA00023; onco-lncRNA-83
|RB samples and corresponding nontumor tissues; Rb cell line WERI-RB1 and Y79
|transfection, qRT-PCR, Western blot, CCK-8 assay, apoptosis assay, luciferase reporter assay
|MEG3 is a tumor suppressor by negatively regulating the activity of the Wnt/β-catenin pathway in the progression of retinoblastoma.
|Decreased expression of MEG3 contributes to retinoblastoma progression and affects retinoblastoma cell growth by regulating the activity of Wnt/β-catenin pathway.
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