| ncRNA name | MEG3 |
| ncRNA Category | lncRNA |
| ID | 55384 |
| Ensembl | ENSG00000214548 |
| Synonyms | GTL2; FP504; prebp1; PRO0518; PRO2160; LINC00023; NCRNA00023; onco-lncRNA-83 |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples and corresponding nontumor tissues; Rb cell line WERI-RB1 and Y79 |
| Methods | transfection, qRT-PCR, Western blot, CCK-8 assay, apoptosis assay, luciferase reporter assay |
| Expression pattern | down-regulated |
| Functional description | MEG3 is a tumor suppressor by negatively regulating the activity of the Wnt/β-catenin pathway in the progression of retinoblastoma. |
| PubMed ID | 26662307 |
| Year | 2016 |
| Title | Decreased expression of MEG3 contributes to retinoblastoma progression and affects retinoblastoma cell growth by regulating the activity of Wnt/β-catenin pathway. |
| Drug-related ncRNA | NO |
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