A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of HOTAIR
ncRNA Category lncRNA
ID 100124700
Ensembl ENSG00000228630
Synonyms HOXC-AS4, HOXC11-AS1, NCRNA00072
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples and adjacent noncancerous tissues; RB cell lines Y79, HXO-Rb44, SO-Rb50 and WERI-RB1
Methods microarray, qRT-PCR, transfection, luciferase reporter assay, colony assay, CCK‐8 assay, apoptosis assay, Western blot
Expression pattern up-regulated
Functional description The role of lncRNA HOTAIR/miR-613/c-met signalling axis in modulating retinoblastoma cells' viability, apoptosis and expressions of EMT-specific proteins might provide evidences for developing appropriate diagnostic and treatment strategies for retinoblastoma.
PubMed ID 30030888
Year 2018
Title LncRNA HOTAIR/miR-613/c-met axis modulated epithelial-mesenchymal transition of retinoblastoma cells.
Drug-related ncRNA NO

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