A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of HOTAIR
ncRNA Category lncRNA
ID 100124700
Ensembl ENSG00000228630
Synonyms HOXC-AS4, HOXC11-AS1, NCRNA00072
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples; RB cell line SO-RB50, Y79 and WERI-RB1
Methods microarray, qRT-PCR, flow cytometry, Western blot
Expression pattern up-regulated
Functional description The lncRNA profile in RB and adjacent normal tissues were compared by microarray analysis. A total of 7 up-regulated (7SK, DNM3OS, MEG3, HIF1A-AS1, CCAT1, HOTAIR and LSINCT5) and 5 down-regulated lncRNAs (H19, PCAT1, RRP1B, BCAR4 and MIR31HG, > 2 fold) we
PubMed ID 28088735
Year 2017
Title Long non-coding RNA CCAT1 promotes human retinoblastoma SO-RB50 and Y79 cells through negative regulation of miR-218-5p.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.