A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of H19
ncRNA name H19
ncRNA Category lncRNA
ID 283120
Ensembl ENSG00000130600
Synonyms ASM, ASM1, BWS, D11S813E, LINC00008, NCRNA00008, PRO2605, WT2
Disease name age-related cataract
Species Homo sapiens
Tissues/Cell_line human lens epithelium samples
Methods lncRNA sequencing, qRT-PCR, transfection, MTT assay, Calcein-AM and proPIdium iodide double staining, Rhodamine 123 and Hoechst double staining, EdU incorporation assay, transwell assay, luciferase reporter assay, Western blot
Expression pattern up-regulated
Functional description We identified 63 differentially expressed lncRNAs, including 37 down-regulated lncRNAs and 26 upregulated lncRNAs (nuclear cataractous versus transparent). H19 regulates HLECs function through miR-675-mediated CRYAA expression.
PubMed ID 30286462
Year 2018
Title Long Non-Coding RNA H19 Regulates Human Lens Epithelial Cells Function.
Drug-related ncRNA NO

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