A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-124
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM samples; UM cell lines OCM-1A, MUM-2C, C918 and MUM-2B ; melanocyte cell line D78
Methods qRT-PCR, transfection, CCK-8 assay, transwell assay, flow cytometry, luciferase reporter assay, Western blot, RNA immunoprecipitation, Chromatin immunoprecipitation
Expression pattern associated
Functional description Our results showed that ectopic miR-124 expression could lead to proliferation and invasion suppression in UM cells.
PubMed ID 28749709
Year 2017
Title LncRNA HOXA11-AS Exerts Oncogenic Functions by Repressing p21 and miR-124 in Uveal Melanoma.
Drug-related ncRNA NO

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