A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-4430
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line dog UM samples
Methods microarray
Expression pattern up-regulated
Functional description Ten of the miRNAs showed increased expression in the metastasizing tumours (with 6 showing >2-fold increase). Class prediction analysis pinpointed 9 miRNAs which categorized tumours as metastasizing or non-metastasizing with an accuracy of 89%. The expression of 4 of the miRNAs was subsequently measured using RT-qPCR, and their up-regulation in metastasizing tumours validated.
PubMed ID 28512868
Year 2018
Title Metastasis-associated microRNA expression in canine uveal melanoma.
Drug-related ncRNA NO

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