A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-140
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM samples and paired normal tissues; UM cell lines MUM-2C, OCM-1A, MUM-2B and C918; melanocyte cell line D78
Methods qPCR, Western blot, MTT assay, colony information asssay, transwell assay
Expression pattern down-regulated
Functional description miR-140 was downregulated in the uveal melanoma tissues compared to normal tissues and cell lines. The expression level of MALAT1 was inversely correlated with the expression level of miR-140 in uveal melanoma tissues.
PubMed ID 27725873
Year 2016
Title Long noncoding RNA MALAT1 promotes uveal melanoma cell growth and invasion by silencing of miR-140.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.