A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-155
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line NK cells; UM cell lines MUM2B, OCM1, NK-92, SKMEL-28, Daudi and K562
Methods immunofluorescence, flow cytometry, qRT-PCR, transfection
Expression pattern up-regulated
Functional description Circulating CD271+ cells from patients with metastatic uveal melanoma manifest cancer stem cell features and express miRs associated with NK cell suppression, including miR-155, that may contribute to metastatic progression.
PubMed ID 27565163
Year 2016
Title Expression of natural killer cell regulatory microRNA by uveal melanoma cancer stem cells.
Drug-related ncRNA NO

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