A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-223
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line plasma
Methods microarray, qRT-PCR
Expression pattern up-regulated
Functional description miR profiling of plasma by a quantitative nuclease protection assay found elevated levels of 11 miRs and reduction in four in patients with tumor monosomy-3. Elevated plasma levels in patients with tumor monosomy-3 of miR-92b, identified in the tumor array, and of miR-199-5p and miR-223, identified in the plasma array, were confirmed by quantitative real-time polymerase chain reaction.
PubMed ID 27453764
Year 2016
Title Association of tumor and plasma microRNA expression with tumor monosomy-3 in patients with uveal melanoma.
Drug-related ncRNA NO

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