A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-335
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line liver perfusate, blood; human malignant melanoma cell line A375; human malignant melanoma cell line MML-1; human breast cancer cell line HTB-133; human lung carcinoma cell line HTB-177; human mast cell line HMC-1.2
Methods flow cytometry, Western blot, qPCR
Expression pattern detectable
Functional description Cluster 2 consisted of seven miRNAs (miR-9*, miR125a-5p, miR-25, miR-125b, miR-335, miR-19a and miR-9) that were also expressed almost equally in patients and the five tested cell lines. KEGG pathway analysis showed that biosynthesis and metabolism pathways, such as “glycosaminoglycan biosynthesis”, “mucin type-O-glycan biosynthesis” and “biotin metabolism”, were among the most common pathways.
PubMed ID 25510783
Year 2014
Title MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma.
Drug-related ncRNA NO

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