A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-25
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line cutaneous melanoma cell line G361; UM cell line OCM-113; normal human epidermal melanocytes (NHEM)
Methods microarray, qPCR
Expression pattern up-regulated
Functional description Among the 28 miRNAs that were upregulated in both cell lines, only 6 miRNAs had been previously reported to function as oncogenic regulators in melanoma. miR-25 is a potential oncogenic miRNA by PTEN targeting in melanoma.
PubMed ID 24675509
Year 2014
Title Identification of microRNA expression patterns in cutaneous and uveal melanoma cell lines.
Drug-related ncRNA NO

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