A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-30d
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line cutaneous melanoma cell line G361; UM cell line OCM-113; normal human epidermal melanocytes (NHEM)
Methods microarray, qPCR
Expression pattern up-regulated
Functional description Among the 28 miRNAs that were upregulated in both cell lines, only 6 miRNAs had been previously reported to function as oncogenic regulators in melanoma. miR-30b/30d upregulation correlated with more advanced tumor stage, metastatic potential, shorter time to recurrence, and reduced overall survival.
PubMed ID 24675509
Year 2014
Title Identification of microRNA expression patterns in cutaneous and uveal melanoma cell lines.
Drug-related ncRNA NO

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