A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA Category lncRNA
ID 100885779
Ensembl ENSG00000258609
Synonyms ROR, lincRNA-RoR, lincRNA-ST8SIA3
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM cell line 92.1, OCM1 and MUM2B; UM samples
Methods RT-PCR, MTT assay, Western blot, immunohistochemical staining, Chromatin immunoprecipitation (ChIP), RNA immunoprecipitation (RIP)
Expression pattern up-regulated
Functional description lncRNA LINC-ROR and its target gene TESC were both significantly upregulated in 3 ocular melanoma cell lines and 20 ocular melanoma specimens compared with normal cells or adjacent normal tissues.
PubMed ID 26169368
Year 2015
Title Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis.
Drug-related ncRNA NO

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