ncRNA name | Robo1 siRNA |
ncRNA Category | siRNA |
Disease name | retinopathy of prematurity (ROP) |
Species | Macaca mulatta |
Tissues/Cell_line | rhesus choroid-retinal endothelial cell line RF/6A |
Methods | siRNA transfection, immunocytochemistry, MTT assay, cell attachment assay, migration assay, flow cytometry, tube formation assay |
Expression pattern | associated |
Functional description | Robo1 expression was elevated in the ROP murine eyes (P < 0.01). Knockdown of Robo1 expression inhibited cell proliferation and migration. Tube formation by RF/6A was also disturbed. |
PubMed ID | 19958120 |
Year | 2009 |
Title | Robo1: a potential role in ocular angiogenesis. |
Drug-related ncRNA | NO |
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