ncRNA name | VEGF siRNA |
ncRNA Category | siRNA |
Disease name | retinopathy of prematurity (ROP) |
Species | Homo sapiens |
Tissues/Cell_line | immature fetal retinal microvascular endothelial cells |
Methods | siRNA transfection, RT-PCR, Western blot, MTT assay |
Expression pattern | associated |
Functional description | VEGF siRNA could down-regulate the expression of VEGF in immature fetal retinal microvascular endothelial cells and suppressed cell proliferation. Application of siRNA to inhibit expression of VEGF may be a hopeful way to prevent and cure ROP. |
PubMed ID | 19951475 |
Year | 2009 |
Title | Effect of vascular endothelial growth factor small interfering RNA (siRNA) on retinal microvascular endothelial cells under hypoxia condition in vitro. |
Drug-related ncRNA | NO |
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