ncRNA name | LPA1 shRNA |
ncRNA Category | shRNA |
Disease name | retinopathy of prematurity (ROP) |
Species | Mus musculus |
Tissues/Cell_line | retinal ganglion cell line RGC-5 |
Methods | shRNA knockdown, Western blot, qPCR |
Expression pattern | associated |
Functional description | Exposure to stearoyl-LPA or hypoxia substantially reduced the viability of RGCs. This was abrogated by THG1603 and shRNA-LPA1. |
PubMed ID | 18978343 |
Year | 2009 |
Title | The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration. |
Drug-related ncRNA | NA |
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