A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-mir-138-5p
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell line Y79; RPE cell line ARPE-19
Methods qRT-PCR, luciferase reporter assay, Western blot, CCK-8 assay, wound healing assay, matrigel assay
Expression pattern down-regulated
Functional description mir-138-5p could repress the development of RB via suppressing PDK1.
PubMed ID 29271995
Year 2017
Title Mir-138-5p acts as a tumor suppressor by targeting pyruvate dehydrogenase kinase 1 in human retinoblastoma.
Drug-related ncRNA NO

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