A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-101
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples, normal retinas; RB cell lines Y79 and WERI-RB1
Methods qRT-PCR, transfection, luciferase reporter assay, MTT assay, colony formation assay, flow cytometry
Expression pattern down-regulated
Functional description Downregulation of miR-101 is associated with tumor aggressiveness in retinoblastoma and inhibits cell growth and proliferation of retinoblastoma cells by targeting EZH2.
PubMed ID 24807198
Year 2014
Title MiR-101, downregulated in retinoblastoma, functions as a tumor suppressor in human retinoblastoma cells by targeting EZH2.
Drug-related ncRNA NO

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