A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-let-7i
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples; RB cell line Y79 and WERI-RB1; breast cancer cell lines MDA-MB-453 and MCF-7; human retinal Müller glial cell line MIO-M1; human thyroid follicular epithelial cell line Nthy-ori 3-1
Methods qRT-PCR
Expression pattern down-regulated
Functional description Let-7 family miRNAs were found to be down regulated in the RB tumors and cell lines.
PubMed ID 24391761
Year 2013
Title Targeted expression of suicide gene by tissue-specific promoter and microRNA regulation for cancer gene therapy.
Drug-related ncRNA NO

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