A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name mmu-let-7b
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Mus musculus
Tissues/Cell_line RB samples, retinas
Methods immunohistochemistry, microarray, qRT-PCR
Expression pattern down-regulated
Functional description miRNA profiling of these tumors identified members of the let-7 and miR-34 families as candidate tumor suppressors in retinoblastoma.
PubMed ID 20019750
Year 2010
Title Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo.
Drug-related ncRNA NO

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