A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name ANRIL
ncRNA Category lncRNA
ID 100048912
Ensembl ENSG00000240498
Synonyms CDKN2B-AS1, CDKN2B-AS, CDKN2BAS, NCRNA00089, PCAT12, RP11-145E5.4, p15AS
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell lines HXO-RB44 and Y79
Methods transfection, qRT-PCR, Western blot, CCK-8 assay, flow cytometry, transwell assay
Expression pattern up-regulated
Functional description ANRIL depletion could act to suppress retinoblastoma progression by activating the ATM-E2F1 signaling pathway.
PubMed ID 30355646
Year 2018
Title The silencing of long non-coding RNA ANRIL suppresses invasion, and promotes apoptosis of retinoblastoma cells through the ATM-E2F1 signaling pathway.
Drug-related ncRNA NO

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