A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name 7SK
ncRNA Category lncRNA
ID 125050
Ensembl ENSG00000283293
Synonyms RN7SK
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB samples; RB cell line SO-RB50, Y79 and WERI-RB1
Methods microarray
Expression pattern up-regulated
Functional description The lncRNA profile in RB and adjacent normal tissues were compared by microarray analysis. A total of 7 up-regulated (7SK, DNM3OS, MEG3, HIF1A-AS1, CCAT1, HOTAIR and LSINCT5) and 5 down-regulated lncRNAs (H19, PCAT1, RRP1B, BCAR4 and MIR31HG, > 2 fold) were identified.
PubMed ID 28088735
Year 2017
Title Long non-coding RNA CCAT1 promotes human retinoblastoma SO-RB50 and Y79 cells through negative regulation of miR-218-5p.
Drug-related ncRNA NO

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