A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinal detachment
ncRNA name Faim2 siRNA
ncRNA Category siRNA
Disease name retinal detachment
Species Mus musculus
Tissues/Cell_line mouse photoreceptor cell line 661W
Methods Western blot, Caspase assay, siRNA transfection
Expression pattern associated
Functional description When the levels of Faim2 were reduced in 661W cells by siRNA knockdown, Fas activating antibody treatment resulted in earlier and more robust caspase activation, and increased cell death.
PubMed ID 23029562
Year 2012
Title ERK-mediated activation of Fas apoptotic inhibitory molecule 2 (Faim2) prevents apoptosis of 661W cells in a model of detachment-induced photoreceptor cell death.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.