ncRNA name | Faim2 siRNA |
ncRNA Category | siRNA |
Disease name | retinal detachment |
Species | Mus musculus |
Tissues/Cell_line | mouse photoreceptor cell line 661W |
Methods | Western blot, Caspase assay, siRNA transfection |
Expression pattern | associated |
Functional description | When the levels of Faim2 were reduced in 661W cells by siRNA knockdown, Fas activating antibody treatment resulted in earlier and more robust caspase activation, and increased cell death. |
PubMed ID | 23029562 |
Year | 2012 |
Title | ERK-mediated activation of Fas apoptotic inhibitory molecule 2 (Faim2) prevents apoptosis of 661W cells in a model of detachment-induced photoreceptor cell death. |
Drug-related ncRNA | NO |
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