A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinal detachment
ncRNA name Cyld shRNA
ncRNA Category shRNA
Disease name retinal detachment
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods shRNA injection, H&E staining, fluorescence detection, PI staining, ERG, immunoprecipitation, Western blot
Expression pattern associated
Functional description Knockdown of cylindromatosis expression led to inhibition of caspase 8 activity, a decrease in the number of apoptotic photoreceptor cells, and an increase in the ubiquitination level of receptor-interacting protein 1.
PubMed ID 28633009
Year 2017
Title RNA Interference Reveals the Coregulatory Effects of Cylindromatosis on Apoptosis and Necroptosis of Photoreceptor Cells in Experimental Retinal Detachment.
Drug-related ncRNA NA

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