A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinal detachment
ncRNA name TRB3 shRNA
ncRNA Category shRNA
Disease name retinal detachment
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods qPCR, Western blot, immunohistochemistry, shRNA knockdown, H&E staining
Expression pattern associated
Functional description TRB3 expression is up-regulated in retinas after RD and knockdown of TRB3 protects photoreceptors against ERS-induced apoptosis.
PubMed ID 25860695
Year 2016
Title Inhibition of TRB3 Protects Photoreceptors against Endoplasmic Reticulum Stress-Induced Apoptosis after Experimental Retinal Detachment.
Drug-related ncRNA NA

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