A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of proliferative vitreoretinopathy (PVR)
ncRNA name PTN siRNA
ncRNA Category siRNA
Disease name proliferative vitreoretinopathy (PVR)
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods intravitreal injection, fundus images
Expression pattern associated
Functional description PTN silencing inhibited the up-regulation of claudin-1 and occludin stimulated by TGF-β1, and PTN knockdown inhibited the proliferative aspects of severe PVR in vivo.
PubMed ID 28083679
Year 2017
Title The effects of pleiotrophin in proliferative vitreoretinopathy.
Drug-related ncRNA NO

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