A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of proliferative vitreoretinopathy (PVR)
ncRNA name PDGF-B siRNA
ncRNA Category siRNA
Disease name proliferative vitreoretinopathy (PVR)
Species Rattus norvegicus
Tissues/Cell_line retinas and the proliferative membranes
Methods siRNA injection, ELISA, RT-PCR
Expression pattern associated
Functional description The combinatorial use of UTMD(ultrasound-targeted microbubble destruction) and rAAV2-mediated RNAi targeting TGF-β2 and PDGF-B can serve as a novel approach to attenuate PVR.
PubMed ID 22499528
Year 2012
Title A novel approach to attenuate proliferative vitreoretinopathy using ultrasound-targeted microbubble destruction and recombinant adeno-associated virus-mediated RNA interference targeting transforming growth factor-β2 and platelet-derived growth factor-B.
Drug-related ncRNA NO

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