ncRNA name | MALAT1 |
ncRNA Category | lncRNA |
ID | 378938 |
Ensembl | ENSG00000251562 |
Synonyms | HCN, LINC00047, MALAT-1, NCRNA00047, NEAT2, PRO1073, mascRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Homo sapiens |
Tissues/Cell_line | PVR vitreous samples; human RPE cell line ARPE-19; human primary RPE cells |
Methods | qRT-PCR, Western blot, immunofluorescence, transwell assay |
Expression pattern | up-regulated |
Functional description | LncRNA MALAT1 is involved in TGFβ1-induced EMT of human RPE cells and provides new understandings for the pathogenesis of PVR. |
PubMed ID | 27019196 |
Year | 2016 |
Title | Long Non-Coding RNA MALAT1 Mediates Transforming Growth Factor Beta1-Induced Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells. |
Drug-related ncRNA | NO |
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