| ncRNA name | hsa-miR-143-3p |
| ncRNA Category | miRNA |
| Disease name | primary open-angle glaucoma (POAG) |
| Species | Homo sapiens |
| Tissues/Cell_line | aqueous humor |
| Methods | TaqMan Low-Density PCR Arrays, qPCR |
| Expression pattern | up-regulated |
| Functional description | Significant up-regulation of miR-518d and miR-143, and significant down-regulation of miR-660, was observed in the AH of POAG patients compared with controls. These miRNAs were predicted to reduce cell proliferation and extracellular matrix remodeling, endocytosis, Wnt signaling, ubiquitin-mediated proteolysis, and adherens junction function. |
| PubMed ID | 28586912 |
| Year | 2017 |
| Title | Comparison of MicroRNA Expression in Aqueous Humor of Normal and Primary Open-Angle Glaucoma Patients Using PCR Arrays: A Pilot Study. |
| Drug-related ncRNA | NO |
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