| ncRNA name | Optineurin siRNA |
| ncRNA Category | siRNA |
| Disease name | primary open-angle glaucoma (POAG) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | rat pheochromocytoma cell line PC12 |
| Methods | siRNA transfection, Transmission electron microscopy, qRT-PCR, Western blot, MTT assay, flow cytometry, microarray |
| Expression pattern | associated |
| Functional description | SiRNA effectively downregulated optineurin expression in RGC-5 and PC12 stable transfected cells. Optineurin siRNA significantly inhibited cell growth and increased apoptosis in RGC-5 and PC12 cells. |
| PubMed ID | 22194658 |
| Year | 2012 |
| Title | Effects of optineurin siRNA on apoptotic genes and apoptosis in RGC-5 cells. |
| Drug-related ncRNA | NO |
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