| ncRNA name | HES1 shRNA |
| ncRNA Category | shRNA |
| Disease name | primary open-angle glaucoma (POAG) |
| Species | Homo sapiens |
| Tissues/Cell_line | primary human trabecular meshwork cells |
| Methods | transduction, Western blot, immunofluorescence, transwell assay, CCK-8 assay, Ki67 staining, Edu assay |
| Expression pattern | associated |
| Functional description | HES1 shRNA abrogated the extracellular matrix protein up-regulation and rescued the functional defects caused by the oxidative stress. |
| PubMed ID | 28423527 |
| Year | 2017 |
| Title | HES1 promotes extracellular matrix protein expression and inhibits proliferation and migration in human trabecular meshwork cells under oxidative stress. |
| Drug-related ncRNA | NA |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.