ncRNA name | HES1 shRNA |
ncRNA Category | shRNA |
Disease name | primary open-angle glaucoma (POAG) |
Species | Homo sapiens |
Tissues/Cell_line | primary human trabecular meshwork cells |
Methods | transduction, Western blot, immunofluorescence, transwell assay, CCK-8 assay, Ki67 staining, Edu assay |
Expression pattern | associated |
Functional description | HES1 shRNA abrogated the extracellular matrix protein up-regulation and rescued the functional defects caused by the oxidative stress. |
PubMed ID | 28423527 |
Year | 2017 |
Title | HES1 promotes extracellular matrix protein expression and inhibits proliferation and migration in human trabecular meshwork cells under oxidative stress. |
Drug-related ncRNA | NA |
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