| ncRNA name | ENST00000607393 |
| ncRNA Category | lncRNA |
| ID | NA |
| Ensembl | ENSG00000272043 |
| Synonyms | AC016405.2 |
| Disease name | primary open-angle glaucoma (POAG) |
| Species | Homo sapiens |
| Tissues/Cell_line | aqueous humor, iris and plasma; primary human trabecular meshwork (HTM) cells |
| Methods | qPCR, microarray, fluorescence in situ hybridization (FISH), RNAi |
| Expression pattern | up-regulated |
| Functional description | qRT-PCR confirmed that T267384, ENST00000607393, and T342877 expression levels were significantly higher in the AH from a different cohort of POAG patients. ENST00000607393 was also significantly higher in the iris and plasma of POAG patients. Last, ENST00000607393 knockdown alleviated calcification of primary human trabecular meshwork cells in vitro. |
| PubMed ID | 30677397 |
| Year | 2019 |
| Title | Potential Biomarkers for Primary Open-Angle Glaucoma Identified by Long Noncoding RNA Profiling in the Aqueous Humor. |
| Drug-related ncRNA | NO |
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