A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of primary open-angle glaucoma (POAG)
ncRNA name ASMM10P055228
ncRNA Category lncRNA
Ensembl NA
Synonyms NA
Disease name primary open-angle glaucoma (POAG)
Species Mus musculus
Tissues/Cell_line retinas
Methods microarray
Expression pattern up-regulated
Functional description Mutations in the optineurin (OPTN) gene, including E50K, which encodes an amino acid substitution, have been associated with primary open angle glaucoma (POAG). A total of 62 lncRNAs showed differential expression between the OPTN (E50K) transgenic mice and wild-type mice, which included 32 downregulated and 30 upregulated lncRNAs.
PubMed ID 29067446
Year 2017
Title Microarray expression profile analysis of long non-coding RNAs in optineurin E50K mutant transgenic mice
Drug-related ncRNA NO

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