A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of primary open-angle glaucoma (POAG)
ncRNA name CDKN2B-AS1
ncRNA Category lncRNA
ID 100048912
Ensembl ENSG00000240498
Synonyms ANRIL; p15AS; PCAT12; CDKN2BAS; CDKN2B-AS; NCRNA00089
Disease name primary open-angle glaucoma (POAG)
Species Homo sapiens
Tissues/Cell_line blood
Methods microarray
Expression pattern associated
Functional description rs10120688. For 9 of the 10 protective CDKN2B-AS1 SNPs with minor alleles associated with reduced disease risk, POAG patients carrying these minor alleles had smaller cup-to-disc ratio despite having higher intraocular pressure (IOP).
PubMed ID 23111177
Year 2013
Title CDKN2B-AS1 genotype-glaucoma feature correlations in primary open-angle glaucoma patients from the United States.
Drug-related ncRNA NO

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