A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of optic nerve injury
ncRNA name Nogo-A siRNA
ncRNA Category siRNA
Disease name optic nerve injury
Species Rattus norvegicus
Tissues/Cell_line optic nerves, retinas
Methods transduction, Western blot
Expression pattern associated
Functional description The integrin signaling pathway is regulated by Amino-Nogo, which inhibits optic nerve regeneration and functional recovery, and that the integrin subunit involved might be integrin αv. Nogo-A siRNA treatment significantly increased integrin αv expression and p-FAK levels.
PubMed ID 25612921
Year 2015
Title Amino-Nogo inhibits optic nerve regeneration and functional recovery via the integrin αv signaling pathway in rats.
Drug-related ncRNA NO

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