A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of optic nerve injury
ncRNA name iASPP siRNA
ncRNA Category siRNA
Disease name optic nerve injury
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods siRNA injection, immunohistochemistry, Western blot, immunoprecipitation
Expression pattern associated
Functional description We show that short interference RNA (siRNA)-induced iASPP knockdown exacerbates RGC death, whereas adeno-associated virus (AAV)-mediated iASPP expression promotes RGC survival.
PubMed ID 24714389
Year 2014
Title Inhibitor of apoptosis-stimulating protein of p53 (iASPP) is required for neuronal survival after axonal injury.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.