ncRNA name | iASPP siRNA |
ncRNA Category | siRNA |
Disease name | optic nerve injury |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | siRNA injection, immunohistochemistry, Western blot, immunoprecipitation |
Expression pattern | associated |
Functional description | We show that short interference RNA (siRNA)-induced iASPP knockdown exacerbates RGC death, whereas adeno-associated virus (AAV)-mediated iASPP expression promotes RGC survival. |
PubMed ID | 24714389 |
Year | 2014 |
Title | Inhibitor of apoptosis-stimulating protein of p53 (iASPP) is required for neuronal survival after axonal injury. |
Drug-related ncRNA | NO |
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