A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of optic nerve injury
ncRNA name sAC siRNA
ncRNA Category siRNA
Disease name optic nerve injury
Species Rattus norvegicus
Tissues/Cell_line retinal ganglion cells (RGCs)
Methods immunocytochemistry, Western blot, RT-PCR, ELISA, siRNA electroporation
Expression pattern associated
Functional description SiRNA-mediated sAC inhibition dramatically decreased RGC survival and axon growth in vitro, and survival in vivo.
PubMed ID 22649251
Year 2012
Title Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth.
Drug-related ncRNA NO

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