ncRNA name | sAC siRNA |
ncRNA Category | siRNA |
Disease name | optic nerve injury |
Species | Rattus norvegicus |
Tissues/Cell_line | retinal ganglion cells (RGCs) |
Methods | immunocytochemistry, Western blot, RT-PCR, ELISA, siRNA electroporation |
Expression pattern | associated |
Functional description | SiRNA-mediated sAC inhibition dramatically decreased RGC survival and axon growth in vitro, and survival in vivo. |
PubMed ID | 22649251 |
Year | 2012 |
Title | Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth. |
Drug-related ncRNA | NO |
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