|optic nerve injury
|retinal ganglion cells (RGCs)
|immunocytochemistry, Western blot, RT-PCR, ELISA, siRNA electroporation
|SiRNA-mediated sAC inhibition dramatically decreased RGC survival and axon growth in vitro, and survival in vivo.
|Soluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth.
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