ncRNA name | CASP2 siRNA |
ncRNA Category | siRNA |
Disease name | optic nerve injury |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | siRNA injection, in situ hybridization, qRT-PCR, Western blot, immunohistochemical analysis |
Expression pattern | associated |
Functional description | RGC apoptosis induced by optic nerve injury involves activation of caspase-2, and that synthetic siRNAs designed to inhibit expression of caspase-2 represent potential neuroprotective agents for intervention in human diseases involving RGC loss. |
PubMed ID | 21677688 |
Year | 2011 |
Title | Ocular neuroprotection by siRNA targeting caspase-2. |
Drug-related ncRNA | NO |
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