A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of optic nerve injury
ncRNA name anti-KLF9 shRNA
ncRNA Category shRNA
Disease name optic nerve injury
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods shRNA injection, immunohistochemistry, MS analysis, IP and Western blot
Expression pattern associated
Functional description We demonstrate that knocking down Krüppel-like transcription factor 9 (KLF9) via shRNA promotes long-distance axon regeneration after optic nerve injury.
PubMed ID 28871032
Year 2017
Title KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS.
Drug-related ncRNA NA

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