A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of optic nerve injury
ncRNA name PTEN shRNA
ncRNA Category shRNA
Disease name optic nerve injury
Species Mus musculus
Tissues/Cell_line optic nerves and retinas
Methods shRNA knockdown, immunohistochemistry, immunocytochemistry, Western blot
Expression pattern associated
Functional description Our data show that adeno-associated virus (AAV) expressing short hairpin RNA (shRNA) against PTEN (shPTEN) enhances retinal ganglion cell axon regeneration after crush injury.
PubMed ID 26005861
Year 2015
Title Viral vector-based improvement of optic nerve regeneration: characterization of individual axons' growth patterns and synaptogenesis in a visual target.
Drug-related ncRNA NA

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