A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of optic nerve injury
ncRNA name Dusp14 siRNA
ncRNA Category siRNA
Disease name optic nerve injury
Species Rattus norvegicus
Tissues/Cell_line retinal ganglion cells (RGCs)
Methods microarray, siRNA transfection, immunohistochemistry, qRT-PCR, Western blot
Expression pattern associated
Functional description Decreasing Dusp14 expression or disrupting its function in RGCs increased axon growth in vitro and promoted survival and optic nerve regeneration after optic nerve injury in vivo.
PubMed ID 29860460
Year 2018
Title The Krüppel-Like Factor Gene Target Dusp14 Regulates Axon Growth and Regeneration.
Drug-related ncRNA NO

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