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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of neuromyelitis optica (NMO)
ncRNA name hsa-miR-454
ncRNA Category miRNA
Disease name neuromyelitis optica (NMO)
Species Homo sapiens
Tissues/Cell_line blood
Methods RNA-seq
Expression pattern up-regulated
Functional description This miRNA was up regulated significantly in the blood of NMO patients following effective therapy with rituximab (all p < 0.05). At the same time, its expression was significantly higher in untreated NMO patients compared with HCs (all p < 0.05).
PubMed ID 27393339
Year 2016
Title Circulating microRNAs as biomarkers for rituximab therapy, in neuromyelitis optica (NMO).
Drug-related ncRNA YES (rituximab)

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