A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of myopia
ncRNA name mmu-miR-141-5p
ncRNA Category miRNA
Disease name myopia
Species Mus musculus
Tissues/Cell_line retinas, scleras
Methods microarray
Expression pattern up-regulated
Functional description We found a total of 53 differentially expressed miRNAs in the retina and no differences in miRNA expression in the sclera of C57BL/6J mice after 10 days of visual form deprivation, which induced -6.93 ± 2.44 D (p < 0.000001, n = 12) of myopia. Thirty seven out of the 53 miRNAs were up-regulated and 16 out of the 53 miRNAs were down-regulated.
PubMed ID 27622715
Year 2016
Title Large-Scale microRNA Expression Profiling Identifies Putative Retinal miRNA-mRNA Signaling Pathways Underlying Form-Deprivation Myopia in Mice.
Drug-related ncRNA NO

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