A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of keratoconus
ncRNA name hsa-miR-184
ncRNA Category miRNA
Disease name keratoconus
Species Homo sapiens
Tissues/Cell_line corneas, ciliary bodies, retinas and trabecular meshwork
Methods DNA-seq, RNA-seq
Expression pattern up-regulated
Functional description Mutation in MIR184 is a rare cause of KC alone and may be more relevant to cases of KC associated with other ocular abnormalities. The increased expression of miR-184 versus miR-205 in normal cornea samples implies a possible role of miR184 in cornea development and/or corneal diseases.
PubMed ID 26380287
Year 2015
Title Screening of the Seed Region of MIR184 in Keratoconus Patients from Saudi Arabia.
Drug-related ncRNA NO

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