A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of keratoconus
ncRNA name hsa-miR-184
ncRNA Category miRNA
Disease name keratoconus
Species Homo sapiens
Tissues/Cell_line peripheral blood leukocytes; human embryonic kidney cell line HEK293T
Methods DNA sequencing, transfection, qRT-PCR
Expression pattern associated
Functional description Two novel heterozygous substitution mutations in MIR184 were identified in two patients with isolated keratoconus: miR-184(+8C>A) and miR-184(+3A>G). Mutations in MIR184 are a rare cause of keratoconus and were found in 2 of 780 (0.25%) cases.
PubMed ID 23833072
Year 2013
Title Mutational analysis of MIR184 in sporadic keratoconus and myopia.
Drug-related ncRNA NO

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