A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of keratoconus
ncRNA name hsa-miR-184
ncRNA Category miRNA
Disease name keratoconus
Species Homo sapiens
Tissues/Cell_line HeLa cells
Methods deep sequencing, immunohistochemical staining, immunoblot
Expression pattern associated
Functional description We found that a mutation in the seed region of miR-184 (MIR184) is responsible for familial severe keratoconus combined with early-onset anterior polar cataract by deep sequencing of a linkage region known to contain the mutation.
PubMed ID 21996275
Year 2011
Title Mutation altering the miR-184 seed region causes familial keratoconus with cataract.
Drug-related ncRNA NO

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